Throughout the centuries, there have been
many scientific discoveries which have played an important role for the
betterment of the world. Although there have also been some that have changed
the world for the worse. Some are well-known
and instantly come to mind when one
is asked to name the most important scientific discoveries of all time, but
there are other weighty discoveries that are more refined in nature - ones that
are easily overlooked, regardless of the tremendous impact they may have had on
the world. One of such discoveries is antibiotics which have revolutionized today’s
medicine. Perhaps my choice will match up with yours, or maybe it will be
vastly different.
The
discovery of antibiotics has proved to be a boon a boon to human welfare but
some also have the opinion that they are the necessary evils. We do have
Alexander Flemming to thank for this discovery back in 1928, when he forgot to
clean up his workstation before going on holiday after which the golden age of
antibiotics started. Antibiotics are the chemical substances which are produced
by various micro-organisms and other living systems and are capable of
inhibiting the growth of or killing bacteria and other micro-organisms.
Before
the discovery of antibiotics, nothing much could be done by anybody and deaths on
large scale were claimed. For instance Streptococcus pyogenes was the cause of half of all post-birth
deaths and Staphylococcus aureus was fatal in 80% of infected wounds and
the tuberculosis and pneumonia bacteria were famous killers. Now, discovery of
antibiotics has enabled the medical line of work to treat these communicable
diseases [3] together with some that were once life threatening. These are also given to cattle to increase
weight gains and for better nourishment.
Antibiotics can be bacteriostatic (bacteria
stopped from multiplying) or bactericidal (bacteria killed). These interfere
with bacterial cell surface, causing a change in their mode of reproduction . Antibiotics comes in quite a lot of forms and
given in various ways such as topical application, orally or as injections.
Other method is parental. Manufacturing of antibiotics is in two ways. One of
them is natural and is known as biosynthesis while other type is synthetic.
Commonly used antibiotics includes Penicillin, Cephalosporin’s, Aminoglycosides,
Tetracycline’s,and Polypeptides Bacitracin.
Now
the question arises that if these are having so advantages then why these are
known as necessary evil. The answer to this lies in the fact that all drugs
have the potential to be both beneficial and harmful. Antibiotics also carry the seeds of their own destruction
as they kill sensitive bacteria, allowing resistant ones to survive, storing up
problems for future treatments. Allergic reactions to antibiotics are usually seen as
rashes, but severe anemia, stomach disorders and deafness can occasionally
result. It was once believed that allergic reactions to antibiotics were
frequent and permanent but now-a-days we can use anti allergics.
The
solution to all such problems is better diagnostics and targeted use of
antibiotics. One should have to act
by practising: "antibiotic stewardship" to choose only those drugs
that are appropriate and known to work for a particular infection; good
infection control; and reducing the number of patients who receive antibiotics
when they don't need them.
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